Pulmonary Talcosis With Intravenous Drug Abuse

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Pulmonary talcosis with intravenous drug abuse.

Talc has been known to cause lung disease, via inhalation or intravenously. A good history along with radiological correlation will often reveal the diagnosis. However, most intravenous drug abusers are reluctant to give a history of exposure, and most diagnoses are made after lung biopsy. We present a case of acute respiratory failure that posed a diagnostic challenge and was diagnosed only af...

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A 38-year-old woman presented to our pulmonology clinic with complaints of progressive dyspnea and dry cough for more than three months. She denied fever or weight loss. On physical examination, she presented as hypoxemic, with a room air oxygen saturation of 92% and an RR of 24 breaths/min. Pulmonary function tests showed that spirometric values were within normal limits, but there was a sligh...

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Successful lung transplantation for talcosis secondary to intravenous abuse of oral drug

Talcosis due to intravenous injection of oral drugs can cause severe pulmonary disease with progressive dyspnea even when drug use is discontinued. We describe a 54-year-old woman with severe emphysema who underwent left lung transplantation. The patient had a remote history of intravenous injection of crushed methylphenidate (Ritalin) tablets. Chest computed tomography showed severe emphysemat...

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Intravascular Talcosis due to Intravenous Drug Use Is an Underrecognized Cause of Pulmonary Hypertension

Intravenous injection of illegal drugs or medications meant for oral administration can cause granulomatous disease of the lung. This intravascular talcosis results in pulmonary fibrosis and pulmonary hypertension. Nine cases of histologically confirmed intravascular talcosis were reviewed with specific attention given to the clinical histories in these patients. Five autopsy cases were include...

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Needle embolism in intravenous drug abuse

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ژورنال

عنوان ژورنال: Respiratory Care

سال: 2013

ISSN: 0020-1324,1943-3654

DOI: 10.4187/respcare.02402